Thirty years of biochemical work on foot-and-mouth disease virus at the Pirbright Institute

Lyophilizing Foot-and Mouth Disease Virus at Low Drying Temperature

Organic Circulation and persistence of Foot – and – Mouth disease virus type O in guinea pig

Since, the most susceptible laboratory animal to Foot–and–Mouth disease virus (FMDV) is guinea pig, and then one milliliter of FMDV type (O) concentrations of 106-106.5 TCID50was inoculated intradermally (ID) to 10 plantar surface of guinea pig (right side). Guinea pig adapted virus has been prepared after generalization phase, and then one milliliter of virus was inoculated intradermally to 30...

Development of an Indirect Enzyme-linked Immunosorbent Assay to Detect Antibodies against Serotype A2013 of Foot and Mouth Disease Virus in Cattle

Foot and mouth disease (FMD) is a contagious animal disease that causes irreparable damage to the economy of countries, including Iran in which this disease is a native one. Among the ways to combat FMD are vaccination and slaughter. Due to the specific situation of Iran, it is not possible to kill infected animals. Therefore, vaccination is the most important way to fight this disease. S...

Rapid and accurate diagnosis of Foot-and-mouth disease virus by Real-time PCR in field samples

During 2010-2011, Real-time PCR procedure was used to detecting FMDV RNA on 147 epithelium samples from the field. In this survey, for Real-time PCR from 3D gene segment as conserve region selected for tracking all of seven serotypes FMDV. The assay detected the viral RNA in all serotypes of FMDV. The rRT-PCR specifically detected FMD virus in sample with greater sensitivity than our convention...

The World Reference Laboratory for Foot and Mouth Disease: a review of thirty-three years of activity (1958-1991).

The range of activities and contributions of the World Reference Laboratory for Foot and Mouth Disease in Pirbright, Surrey, United Kingdom, from 1958 to 1991 is reviewed. The countries for which a service has been provided, the number of samples submitted for investigation and the serotypes identified are recorded. Factors which have influenced the number of samples received are outlined. The ...